A monthly web conference : 27/11/25 : Sepsis phenotype by Prof. Tom van der Poll (Amsterdam UMC, The Netherlands)
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to an infection. This definition fails to grasp the heterogeneous nature and the underlying dynamic pathophysiology of the syndrome. In response to this heterogeneity, efforts have been made to stratify sepsis patients into distinct phenotypes, either based on their clinical presentation or pathophysiological characteristics. Subtyping of sepsis patients introduces the possibility of the implementation of personalized medicine, whereby each patient receives treatment tailored to their individual disease manifestation.
ParisSepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to an infection. This definition fails to grasp the heterogeneous nature and the underlying dynamic pathophysiology of the syndrome. In response to this heterogeneity, efforts have been made to stratify sepsis patients into distinct phenotypes, either based on their clinical presentation or pathophysiological characteristics. Subtyping of sepsis patients introduces the possibility of the implementation of personalized medicine, whereby each patient receives treatment tailored to their individual disease manifestation.